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Diphtheria


Cause: Toxigenic strains of the bacterium Corynebacterium diphtheriae.

Illness and treatment: Classic diphtheria is an upper-respiratory tract illness characterized by sore throat, low-grade fever, and an adherent membrane of the tonsil(s), pharynx, and/or nose, sometimes with neck swelling. Diphtheria can involve almost any mucous membrane and may also be cutaneous. Treatment is with antitoxin, antibiotics, and supportive care.

Sources:  Humans carriers are the reservoir and are usually asymptomatic. Transmission is through respiratory droplets, but may occur from skin lesions or articles soiled with discharges.

Additional risks: Susceptible travelers to areas where routine immunization of adults is lacking are at higher risk for diphtheria infection, especially if an epidemic is in progress.

Prevention: Universal immunization including booster doses prevents infection. Respiratory and hand hygiene prevent transmission.

Recent Washington trends:  The last recorded case was in 1981.

2010: No cases were reported.

Purpose of Reporting and Surveillance

  • To assist in the diagnosis of cases
  • To assure early and appropriate treatment with diphtheria antitoxin and antibiotics
  • To identify and evaluate contacts and recommend appropriate antibiotic prophylaxis and/or immunization to prevent further spread of the disease
  • To alert public health authorities to the presence of diphtheria cases and the possibility of additional cases developing in the area, a particular concern given the large number of susceptible adults

Legal Reporting Requirements

  • Health care providers: immediately notifiable to local health jurisdiction.
  • Health care facilities: immediately notifiable to local health jurisdiction.
  • Laboratories: Corynebacterium diphtheriae immediately notifiable to local health jurisdiction, specimen submission required - culture (2 business days).
  • Local health jurisdictions: immediately notifiable to the Washington State Department of Health (DOH) Communicable Disease Epidemiology (CDE).

Last update
December 2011

Diphtheria Resources

General Information

Case Definition
(PDF Format)
Diphtheria Incidence Rates
(PDF Format)

Reporting Forms

Diphtheria Reporting Form
(PDF Format)

Public Health and Health Care

Surveillance and Reporting Guidelines
(PDF Format)

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Washington State Department of Health
Communicable Disease Epidemiology
MS: K17-9, 1610 NE 150th Street
Shoreline, WA 98155

Consultation and technical assistance are available to local health jurisdictions in Washington State:
Phone (206) 418-5500

FAX (206) 418-5515

24-hour contact (inside Washington State only)  1-877-539-4344

Washington residents can contact their local health jurisdictions for assistance


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