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Shellfish Poisoning (Paralytic, Domoic Acid)


Cause: Ingestion of shellfish with a toxin from the phytoplankton Alexandrium catenella for paralytic shellfish poisoning (PSP), ingestion of shellfish with a toxin from marine diatoms Pseudo-nitzschia for domoic acid shellfish poisoning (DASP).

Illness and treatment: PSP symptoms begin minutes or hours after eating contaminated shellfish and may include numbness of the mouths and limbs. Severe PSP progresses rapidly to paralysis and respiratory arrest, and may require mechanical ventilation.  For DASP gastrointestinal symptoms begin within 24 hours of ingestion and may be followed within 48 hours by neurological symptoms including confusion, short-term memory loss, seizures, respiratory secretions, and coma.  There is no anti-toxin for either.

Sources: Bivalve mollusks such as clams, oysters, mussels, and geoduck concentrate PSP toxin. Razor clams, other bivalve mollusks, and Dungeness crab concentrate DASP toxin. There is no person-to-person spread.

Additional risks: PSP is only rarely associated with reddish discoloration of the water, although the term “red tide” is popularly used. Either toxin can be present in dangerous amounts even when the harvest site water looks clean. Freezing or cooking does not destroy the toxins.

Prevention: Before harvesting shellfish check the Marine Biotoxin Hotline (1-800-562-5632) or web site for updates on affected sites and site closures, which may not always have signs posted.

Recent Washington trends: Two clusters of PSP have been reported during the past 10 years (7 reports in 2000 and 5 in 1998). Both clusters were associated with mussels gathered recreationally from south Puget Sound waters.

2010: No cases were reported.

Purpose of Reporting and Surveillance

  • To identify whether the source of transmission is a major pubic health concern (e.g., a commercial shellfish product or recreational harvest area) and to prevent further transmission from such sources.
  • To identify others who shared the exposure and educate them regarding symptoms of paralytic shellfish poisoning to facilitate rapid diagnosis.
  • When the source is a risk to only a few individuals (e.g., shellfish harvested from an area closed to harvesting), to inform those individuals how they can reduce their risk of future exposure.

Legal Reporting Requirements

  • Health care providers: immediately notifiable to local health jurisdiction.
  • Health care facilities: immediately notifiable to local health jurisdiction.
  • Laboratories: no requirements for reporting.
  • Local health jurisdictions: immediately notifiable to the Washington State Department of Health (DOH) Communicable Disease Epidemiology (CDE) (1-877-539-4344 or 206-418-5500).

Last update
December 2011

Shellfish Poisoning Resources

General Information
Case Definition
(PDF Format)
Fact Sheet
(Web Format)
Shellfish Poisoning Incidence Rates
(PDF Format)
Reporting Forms
Shellfish Poisoning Reporting Form
(PDF Format)
Public Health and Health Care
Surveillance and Reporting Guidelines
(PDF Format)

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Washington State Department of Health
Communicable Disease Epidemiology
MS: K17-9, 1610 NE 150th Street
Shoreline, WA 98155

Consultation and technical assistance are available to local health jurisdictions in Washington State:
Phone (206) 418-5500

FAX (206) 418-5515

24-hour contact (inside Washington State only)  1-877-539-4344

Washington residents can contact their local health jurisdictions for assistance


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