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Shiga toxin-producing E. coli (STEC)


Cause: Shiga toxin-producing E. coli strains (STEC) including E. coli O157:H7.

Illness and treatment: Symptoms include abdominal cramping and severe or bloody diarrhea, usually without fever. Serious complications include hemolytic uremic syndrome (HUS) or thrombotic thrombocytopenic purpura (TTP). Most persons will recover without treatment. Treating EHEC diarrhea with antibiotics may increase the risk of developing HUS.

Sources: Cattle are the most important source, although other herbivores may also carry EHEC. Other known sources are unpasteurized milk, undercooked ground beef and contaminated raw produce. There can be person-to-person and animal-to-person transmission, but most cases are due to ingesting contaminated food or water.

Additional risks: Children under 5 years of age are diagnosed most frequently and are at the greatest risk of developing HUS.

Prevention: Wash hands thoroughly after contact with farm animals, visiting farm environments, and handling raw meat. Thoroughly cook ground beef and venison and wash preparation areas to avoid contaminating other foods. Wash produce thoroughly before eating.

Recent Washington trends: For the past several years there have been about 130 - 200 reports each year. EHEC has a seasonal pattern. Most cases occur during summer and fall months.

2010: A total of 226 EHEC cases were reported (rate 3.4 cases/100,000 population); 12 reported HUS as a complication. Among 186 confirmed cases only 110 (59%) were serogroup O157. A recent substantial rate increase for non-O157 EHEC (1.1 in 2010 vs. 0.5 in 2009) reflects new laboratory testing practices. The 76 non-O157 EHEC infections included 45 serogroup O26, 12 O103, 6 O121, and 3 each O111 and O45, and ≤ 2 cases each included O118, O145, O126, O174, and O178.

Purpose of Reporting and Surveillance

  • To determine if there is a source of infection of public health concern (e.g., contaminated ground beef) and to stop transmission from such a source.
  • When the source of infection appears to pose a risk to only a few individuals (e.g., a private water supply), to inform those individuals how they can reduce their risk of exposure.
  • To assess the risk of the case transmitting infection to others, and to prevent such transmission.
  • To identify outbreaks and other undiagnosed cases.

Legal Reporting Requirements

  • Health care providers: immediately notifiable to local health jurisdiction
  • Health care facilities: immediately notifiable to local health jurisdiction
  • Laboratories: Shiga toxin-producing E. coli (enterohemorrhagic E. coli including, but not limited to, E. coli O157:H7) and Shiga-toxin positive stool assays immediately notifiable to local health jurisdiction; submission of stool specimen or isolate to the Washington State Department of Health (DOH) Public Health Laboratories (PHL) is required (2 business days)
  • Veterinarians: Suspected human cases immediately notifiable to the local health jurisdiction; animal cases may be notifiable to Washington State Department of Agriculture (see: http://apps.leg.wa.gov/WAC/default.aspx?cite=16-70.)
  • Local health jurisdictions: notifiable to DOH Communicable Disease Epidemiology (CDE) within 7 days of case investigation completion or summary information required within 21 days

Last update
December 2011

STEC Resources

General Information
Case Definition
(PDF Format)
Fact Sheet
(Web Format)
E. coli Incidence Rates
(PDF Format)
Reporting Forms
STEC Reporting Form
(PDF Format)
STEC Supplemental Food History Form
(PDF Format)
Public Health and Health Care
Surveillance and Reporting Guidelines
(PDF Format)

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