For updates on all therapeutic products visit the ASPR COVID-19 website.
Paxlovid and Lagevrio (molnupiravir) are therapeutic products that have received Emergency Use Authorizations (EUA) from the U.S. Food and Drug Administration (FDA). Veklury (remdesivir) is an antiviral drug that has been approved by the U.S. FDA. All are for the treatment of mild to moderate COVID-19 in non-hospitalized patients with laboratory-confirmed SARS-CoV-2 infection who are at high risk for progressing to severe disease and/or hospitalization. Veklury can also be used for hospitalized individuals. Distribution for Paxlovid and Lagevrio (molnupiravir) is provided by the U.S. Health and Human Services and facilitated by the Washington State Department of Health.
Monoclonal Antibodies (mAbs)
Monoclonal antibodies are laboratory-made proteins that mimic the immune system's ability to fight off harmful antigens. Currently, there are no mAbs authorized for emergency use. Check the ASPR website for the current therapeutic products available.
Oral antivirals can only be prescribed by a licensed healthcare provider. Two products have been granted EUAs by the FDA:
- Lagevrio/molnupiravir (Merck) – This works by incorporating into viral RNA and causing mutations that disrupt replication.
- Paxlovid (Pfizer) – This is an antiviral therapy that consists of two separate medications: nirmatrelvir and ritonavir. The former is a protease inhibitor that prevents replication; the latter is also a protease inhibitor that slows the breakdown of nirmatrelvir.
Find Providers with COVID-19 Therapeutics
The COVID-19 Therapeutic Locator map provided by HHS displays locations that have received shipments of U.S. Government-procured COVID-19 therapeutics under the U.S Food and Drug Administration (FDA) Emergency Use Authorization (EUA) authority. The locations displayed in the locator have reported stock on hand within the last two weeks.
Free Telehealth for COVID-19 Treatment
Telehealth is a free and easy way to see if COVID-19 oral antivirals such as Paxlovid are right for you. Oral antivirals, which are COVID-19 treatment pills taken by mouth, are available by prescription only. They must be taken within the first five days of experiencing COVID-19 symptoms and testing positive for COVID-19.