Lynch Syndrome

What is Lynch Syndrome?

Lynch syndrome is a hereditary condition that leads to increased risks for colorectal, endometrial, ovarian and gastric cancers, among others. It is estimated that up to 1 out of 279 individuals has Lynch syndrome but 98% are undiagnosed. Per that estimate, there are approximately 26,000 individuals with undiagnosed Lynch syndrome in Washington State.

A complete diagnosis including genetic testing is crucial not only for tailoring individual preventative treatment but also to give patients the vital risk information to share with their family members (a process known as cascade screening). They too may take action to prevent future Lynch syndrome-related cancers.

For you

2014 Screening and Genetics Survey Results (PDF)
A summary of a survey completed by Washington state and Oregon gastroenterologists

Lynch Syndrome Fact Sheet for Providers (PDF)
A quick guide on Lynch syndrome

Cascade Screening: A Critical Step in diagnosing Lynch Syndrome (PDF)
A guide for diagnosing asymptomatic family members

Cancer Genetic Clinics Contact Information (PDF)
References for Washington

Cancer Genetic Clinic Locations and Hereditary Cancer Case Burden by County in Washington State (PDF)
To identify possible gaps in access to services, cancer cases meeting high-risk criteria for hereditary cancer syndromes were identified from one year of Washington State Cancer Registry data and counts per county mapped with Regional Genetic Clinics that provide cancer genetic services.

Additional Resources for Providers

For Your Patient and their Families

Collecting Your Cancer Family History (PDF)

Cancer Family History Questionnaires
Forms to assist patients with family history information and assess risk for colorectal cancer

Patient Resources

Involving the patient in the process

Genetic Testing & Cancer Prevention for Lynch Syndrome
English (PDF) | Spanish (PDF)

Lynch Syndrome
English (PDF) | Spanish (PDF)

Talking to Family About Lynch Syndrome
English (PDF) | Spanish (PDF)

Cancer Can Run in the Family (PDF)

Cascade Screening: infographic (PDF)

Letter to Relatives Template (PDF)
A tool to help patients begin the conversation with family members

Additional Resources for Patients (PDF)

Contact the Screening and Genetics Unit at if you have questions about Lynch syndrome or would like more information.